当前位置: X-MOL 学术Green Synth. Catal. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Pd-catalyzed enantioselective intramolecular Heck reaction to access disubstituted dihydroisoquinolinone with a terminal olefin
Green Synthesis and Catalysis ( IF 8.2 ) Pub Date : 2021-11-1 , DOI: 10.1016/j.gresc.2021.10.006
Sanliang Li , Qiaoyu Chen , Zhan-Ming Zhang , Junliang Zhang

A first palladium-catalyzed asymmetric intramolecular Heck reaction for the construction 3,4-dihydro-1-(2H)-isoquinolinone containing the quaternary carbon chiral center has been developed. The salient features of this reaction include high efficiency, high enantioselectivity, the novel chiral ligand and diverse transformations.

中文翻译:

Pd催化的对映选择性分子内Heck反应获得具有末端烯烃的二取代二氢异喹啉酮

开发了第一个钯催化的不对称分子内 Heck 反应,用于构建含有季碳手性中心的 3,4-二氢-1-(2H)-异喹啉酮。该反应的显着特点包括高效、高对映选择性、新型手性配体和多种转化。
更新日期:2022-01-13
down
wechat
bug