Patient-reported outcome measures (PROMs) are frequently used to assess treatment outcomes for hand and wrist conditions. To adequately interpret these outcomes, it is important to determine whether a statistically significant change is also clinically relevant. For this purpose, the minimally important change (MIC) was developed, representing the minimal within-person change in outcome that patients perceive as a beneficial treatment effect. Prior studies demonstrated substantial differences in MICs between condition-treatment combinations, suggesting that MICs are context-specific and cannot be reliably generalized. Hence, a study providing MICs for a wide diversity of condition-treatment combinations for hand and wrist conditions will contribute to more accurate treatment evaluations.

中文翻译：

---

对于 36 种手部和手腕状况治疗组合，四种常用的患者报告结果测量的最轻微的重要变化是什么？

患者报告的结果测量 (PROM) 经常用于评估手部和腕部疾病的治疗结果。为了充分解释这些结果，重要的是确定统计上显着的变化是否也具有临床相关性。为此，开发了最小重要变化（MIC），代表患者认为有益的治疗效果的最小个人结果变化。先前的研究表明，不同条件治疗组合之间的 MIC 存在显着差异，这表明 MIC 是针对具体情况的，不能可靠地概括。因此，一项为手部和腕部疾病提供多种疾病治疗组合的 MIC 的研究将有助于更准确的治疗评估。