Highly controllable and efficient crystallization process is the urgent requirement for hyper pure solid product and the green process engineering. Especially, the accurate regulation of the microscale nucleation and intensification of crystal growth is multidisciplinary and multiscale topic that has attracted many researchers’ attention. Herein, this review will systematically discuss the principle of membrane crystallization, as a novel microscale interfacial technology, on the interfacial supersaturation control, nucleation, particle motion and growth in the hybrid process. The controlling theory based on microscale pores and channels of the membrane interface and further applications based on membrane crystallization technology are then emphasized. Finally, as an emerging technology, the perspectives and key research directions in membrane crystallization are outlined for the advanced crystallization engineering.

高度可控、高效的结晶过程是超纯固体产品和绿色工艺工程的迫切要求。尤其是微尺度成核和晶体生长强化的精确调控是一个多学科、多尺度的课题，引起了众多研究者的关注。在此，本综述将系统地讨论膜结晶作为一种新型微尺度界面技术，在混合过程中的界面过饱和控制、成核、粒子运动和生长的原理。然后重点介绍了基于膜界面微孔和通道的控制理论以及基于膜结晶技术的进一步应用。最后，作为一项新兴技术，