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Synthesis of indole based novel symmetrical nitroolefinic dendritic core through n-arylation route
Indian Journal of Chemical Technology ( IF 0.5 ) Pub Date : 2021-12-24
V Sathya, N Venkatesan, T R Heera, M N Sivakumar

Synthesis of indole based novel symmetrical nitroolefinic dendritic core has been succeeded using N-arylation route followed by Henry reaction. Synthesized symmetrical 1,3,5-triindolyl benzene has been successfully synthesis of by N-arylation of indole, symmetrical 1,3,5-tri(3-formyl indolyl)benzene and 1,3,5-tris(3-((E)-2-nitrovinyl)-1H-indol-1yl)benzene followed by Hendry reaction. These nitroolefinic cores have potential application in theoretical and medicinal chemistry and also used to prepare many new organic compounds of indole derivatives.

中文翻译:

n-芳基化路线合成吲哚基新型对称硝基烯烃树枝状核

已经使用 N-芳基化路线和亨利反应成功合成了基于吲哚的新型对称硝基烯烃树枝状核。合成的对称1,3,5-三吲哚苯已通过吲哚的N-芳基化、对称1,3,5-三(3-甲酰基吲哚基)苯和1,3,5-三(3-(( E)-2-硝基乙烯基)-1H-吲哚-1基)苯,然后进行亨德利反应。这些硝基烯烃核在理论和药物化学方面具有潜在的应用价值,还用于制备许多吲哚衍生物的新型有机化合物。
更新日期:2021-12-24
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