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Role of Polygenic Risk Score in the Familial Transmission of Bipolar Disorder in Youth
JAMA Psychiatry ( IF 22.5 ) Pub Date : 2022-02-01 , DOI: 10.1001/jamapsychiatry.2021.3700
Boris Birmaher 1 , Danella Hafeman 1 , John Merranko 1 , Alyson Zwicker 2, 3 , Benjamin Goldstein 4 , Tina Goldstein 1 , David Axelson 5 , Kelly Monk 1 , Mary Beth Hickey 1 , Dara Sakolsky 1 , Satish Iyengar 6 , Rasim Diler 1 , Vishwajit Nimgaonkar 6 , Rudolf Uher 7
Affiliation  

This case-control study evaluated whether parents with bipolar disorder and their offspring had specifically increased bipolar disorder polygenic risk scores compared with polygenic risk scores for depression, schizophrenia, and attention-deficit/hyperactivity disorder.

中文翻译:

多基因风险评分在青少年双相情感障碍家族传播中的作用

这项病例对照研究评估了与抑郁症、精神分裂症和注意力缺陷/多动障碍的多基因风险评分相比,患有双相情感障碍的父母及其后代是否具有特异性增加的双相情感障碍多基因风险评分。
更新日期:2022-02-03
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