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Chiral resolution of DL-glutamic acid by a chiral additive
Journal of Chemical Technology and Biotechnology ( IF 2.8 ) Pub Date : 2021-12-22 , DOI: 10.1002/jctb.7018
Xin‐hui Zhou 1 , Qing Liu 2 , Hai‐shui Wang 1
Affiliation  

Enantiomerically pure compounds occupy an important position in industrial production of pharmaceuticals, food, chemical engineering, etc. The separation of d and l molecules is an important and challenging task. The ‘tailor-made’ additive method is a simple and efficient crystallization separation technology. However, according to reports, there is a poor crystal yield when obtaining a relatively ideal enantiopurity and vice versa. Furthermore, the crystallization time always needs to be controlled strictly.

中文翻译:

手性添加剂手性拆分 DL-谷氨酸

对映体纯化合物在医药、食品、化工等工业生产中占有重要地位。d分子和l分子的分离是一项重要而具有挑战性的任务。“量身定做”的添加剂法是一种简单高效的结晶分离技术。然而,据报道,在获得相对理想的对映体纯度时晶体产率较差,反之亦然。此外,结晶时间总是需要严格控制。
更新日期:2021-12-22
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