Purpose. High-normal blood pressure has been suggested to associate with target organ damage and higher left ventricular mass index (LVMI). Our aim is to find the association between people with high-normal blood pressure and their left ventricular mass index. Materials and Methods. Given a total of 181 people with office blood pressure, 24-hour ambulatory blood pressure monitoring, 35 of them are normotensive (BP < 130/85 mm Hg), and 146 people with high-normal blood pressure (BP 130–139/85–89 mm Hg), divide the high-normal blood pressure group into dipper and nondipper according to their ABPM in 24 hours. All of them were performed with echocardiography to calculate LVMI. Results. After adjusting for potential confounding factors, mean systolic blood pressure (BP) of the nondipper group is (119 + 9) mmHg in 24 h, which is significantly higher ( < 0.05) than in the dipper group (116 + 11) mmHg, indicating the mean systolic BP is associated with the dipper type ( < 0.05); furthermore, the higher nocturnal blood pressure is associated with the nondipper group significantly ( < 0.05), and LVMI ((121 ± 11) g/m²) of the nondipper group is also significantly higher than in the dipper group’s LVMI ((108 ± 12) g/m²) ( < 0.05). The multivariate linear regression analyses revealed significant and independent associations of LVMI with these factors: triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL-C), and coefficient of variation of systolic and diastolic blood pressure in 24 hours. Conclusion. After multiple relevant clinical confounding factors were adjusted, patients with dipper and nondipper high-normal blood pressure had higher LVMI. Abnormalities in circadian blood pressure variability may be associated with the left ventricular hypertrophy.

中文翻译：

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Dipper 和 Nondipper 高正常血压患者与左心室肿块相关

目的。高正常血压被认为与靶器官损伤和较高的左心室质量指数（LVMI）有关。我们的目标是找出正常血压偏高的人与其左心室质量指数之间的关联。材料和方法。共有 181 人有办公室血压，24 小时动态血压监测，其中 35 人血压正常（BP < 130/85 mm Hg），146 人血压正常高（BP 130-139/85 –89 mm Hg），根据24小时的ABPM将正常高血压组分为杓型和非杓型。所有这些都用超声心动图来计算LVMI。结果. 调整潜在混杂因素后，非杓型组 24 小时平均收缩压（BP）为（119+9）mmHg，显着高于 杓型组（116+11）mmHg（<0.05），表明平均收缩压与杓型相关（ <0.05）；此外，较高的夜间血压与非杓型组显着相关（ <0.05），非杓型组的LVMI（（121±11）g/m ²）也显着高于型组的LVMI（（108± 12) 克/平方米² ) ( < 0.05)。多元线性回归分析显示 LVMI 与以下因素显着且独立相关：甘油三酯 (TG)、总胆固醇 (TC)、低密度脂蛋白 (LDL-C) 以及 24 小时内收缩压和舒张压的变异系数. 结论。调整多个相关临床混杂因素后，杓型和非杓型正常高血压患者的LVMI较高。昼夜血压变异性异常可能与左心室肥大有关。