The emergence and prevalence of bacterial pathogens in freshwater aquaculture systems is a growing concern as the economic losses associated with diseases are mounting and impacting the fishery sector. One way of controlling fish mortality and morbidity is using bacteriocin-secreting probiotics, which are generally considered safe without any adverse effects that usually accompany other treatment strategies. Understanding the mode of action of bacteriocin on pathogens is vital for considering them suitable for application as a prophylactic in aquaculture. Although several measures such as antibiotic treatment, chemotherapy, vaccination, etc., are available, though not without concerns, these methods have limitations for field-level applications since they result in several adverse effects both for the animals and the aquatic environment affecting several species in the food chain. In this situation, the use of bacteriocin can be an excellent alternative to minimize the disease burden in freshwater aquaculture if delivered appropriately. Here, we provide an update on the various bacteriocins and their mode of action against important pathogens encountered in aquaculture.

中文翻译：

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细菌素在可持续水产养殖中的潜在应用

随着与疾病相关的经济损失不断增加并影响渔业部门，淡水水产养殖系统中细菌病原体的出现和流行日益受到关注。控制鱼类死亡率和发病率的一种方法是使用分泌细菌素的益生菌，这种益生菌通常被认为是安全的，没有任何通常伴随其他治疗策略的副作用。了解细菌素对病原体的作用方式对于考虑它们是否适合在水产养殖中用作预防剂至关重要。尽管有几种措施，如抗生素治疗、化学疗法、疫苗接种等，但并非没有顾虑，这些方法在田间应用方面存在局限性，因为它们会对动物和水生环境造成若干不利影响，影响食物链中的若干物种。在这种情况下，如果使用得当，使用细菌素可以成为减轻淡水水产养殖疾病负担的绝佳选择。在这里，我们提供了有关各种细菌素及其对水产养殖中遇到的重要病原体的作用方式的最新信息。