Supercritical fluid adsorption (SFA) is a feasible and novel technique that combines the adsorption process with supercritical fluid technology. Nowadays, two techniques originating from SFA are being investigated, supercritical fluid chromatography (SFC) and supercritical fluid impregnation (SFI). SFC aims to achieve a higher concentration of the target compounds or remove undesirable substances through a chromatographic column. SFI aims to impregnate the target compounds in porous materials to protect them against degradation and to promote their controlled release. This work reviews the main applications of SFA in the natural extracts field. First, the principles, technical and practical aspects of supercritical adsorption processes are addressed. Next, a critical review of the literature from the last 15 years on the SFC and SFI processes of natural extracts is presented, emphasizing SFC in semi- and preparative scales and the use of SFI for the development of food packaging and drug delivery of bioactive compounds. Adsorption isotherms are reported for mono-component and multi-component systems. Moreover, the integration between SFA and other high-pressure processes is described and exemplified for natural extracts. Finally, emerging topics and potential opportunities for future innovations are outlined.

超临界流体吸附（SFA）是一种将吸附过程与超临界流体技术相结合的可行且新颖的技术。目前，正在研究源自 SFA 的两种技术，超临界流体色谱 (SFC) 和超临界流体浸渍 (SFI)。SFC 旨在通过色谱柱实现更高浓度的目标化合物或去除不需要的物质。SFI 旨在将目标化合物浸渍在多孔材料中，以保护它们免受降解并促进其受控释放。这项工作回顾了 SFA 在天然提取物领域的主要应用。首先，讨论了超临界吸附过程的原理、技术和实践方面。下一个，对过去 15 年关于天然提取物的 SFC 和 SFI 工艺的文献进行了批判性回顾，强调半和制备规模的 SFC 以及 SFI 在食品包装和生物活性化合物药物输送的开发中的应用。报告了单组分和多组分系统的吸附等温线。此外，还描述并举例说明了 SFA 与其他高压工艺之间的整合，用于天然提取物。最后，概述了新兴主题和未来创新的潜在机会。描述并举例说明了天然提取物的 SFA 与其他高压工艺之间的整合。最后，概述了新兴主题和未来创新的潜在机会。描述并举例说明了天然提取物的 SFA 与其他高压工艺之间的整合。最后，概述了新兴主题和未来创新的潜在机会。