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Biomaterial strategies for the application of reproductive tissue engineering
Bioactive Materials ( IF 20.3 ) Pub Date : 2021-12-20 , DOI: 10.1016/j.bioactmat.2021.11.023
Xuemin Liu Kai Wu Liang Gao Liping Wang Xuetao Shi

Human reproductive organs are of vital importance to the life of an individual and the reproduction of human populations. So far, traditional methods have a limited effect in recovering the function and fertility of reproductive organs and tissues. Thus, aim to replace and facilitate the regrowth of damaged or diseased tissue, various biomaterials are developed to offer hope to overcome these difficulties and help gain further research progress in reproductive tissue engineering. In this review, we focus on the biomaterials and their four main applications in reproductive tissue engineering: in vitro generation and culture of reproductive cells; development of reproductive organoids and models; in vivo transplantation of reproductive cells or tissues; and regeneration of reproductive tissue. In reproductive tissue engineering, designing biomaterials for different applications with different mechanical properties, structure, function, and microenvironment is challenging and important, and deserves more attention.



中文翻译:

生殖组织工程应用的生物材料策略

人类生殖器官对个体的生命和人口的繁衍至关重要。迄今为止,传统方法在恢复生殖器官和组织的功能和生育能力方面效果有限。因此,为了替代和促进受损或患病组织的再生,开发了各种生物材料以提供克服这些困难的希望,并有助于在生殖组织工程方面取得进一步的研究进展。在这篇综述中,我们关注生物材料及其在生殖组织工程中的四个主要应用:生殖细胞的体外生成和培养;开发生殖类器官和模型;生殖细胞或组织的体内移植;和生殖组织的再生。在生殖组织工程中,

更新日期:2021-12-20
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