Over the past decades, the rapid population growth coupled with increased awareness towards nutrition has driven the demand for organic acids (e.g., carboxylates) and proteins, through pharmaceutical and food products. Close to 50–70% of the overall production cost of organic acids and proteins comes from separation processes during manufacturing. Recently, electrochemically-mediated separations have gained significant attention as a sustainable solution for lowering chemical consumption and achieving process intensification. Here, we review progress in electrochemical processes for the recovery of organic acids and proteins, in food and biomanufacturing contexts. We highlight aspects of the electrochemical engineering of these systems, selection of electrode materials, and discuss the underlying separation mechanisms. We emphasize the need for understanding molecular level selectivity coupled with engineering design, for broadening the applicability of electrochemical platforms for selective bioproduct purification. On the long term, we envision electrochemical separations as a sustainable and competitive process for the recovery of value-added molecules in food and biomanufacturing.

在过去的几十年里，人口的快速增长以及对营养意识的提高推动了对有机酸（例如，羧酸盐）和蛋白质的需求，通过药物和食品。有机酸和蛋白质总生产成本的近 50-70% 来自制造过程中的分离过程。最近，电化学介导的分离作为降低化学品消耗和实现过程强化的可持续解决方案受到了广泛关注。在这里，我们回顾了在食品和生物制造环境中回收有机酸和蛋白质的电化学过程的进展。我们重点介绍了这些系统的电化学工程、电极材料的选择，并讨论了潜在的分离机制。我们强调需要了解分子水平的选择性以及工程设计，以扩大电化学平台在选择性生物产品纯化中的适用性。从长远来看，我们将电化学分离视为食品和生物制造中回收增值分子的可持续且具有竞争力的过程。