This study aimed to develop a method, followed by gas chromatography-mass spectrometry, for detecting 37 pesticides in Chrysanthemum indicum (C. indicum) and investigating the decrease in the matrix-induced enhancement effect. The influence of QuEChERS extraction and matrix solid-phase dispersion (MSPD) on the recovery and matrix effect (ME) was compared. extraction and matrix solid-phase dispersion (MSPD) on the recovery and matrix effect (ME) was compared to decrease the ME. The cleanup sorbents, volume and type of solvent, and treatment time were optimized. The accuracy (as recovery), precision (as relative standard deviation, RSD), linearity, limit of quantitation, and limit of detection were determined. The recoveries at the three levels using mixed standard solution ranged between 76% and 120% with RSD ≤15%, and 76% and 120% with RSD ≤11% for MSPD and QuEChERS extraction, respectively. The results suggested that the ME for 21 pesticides was in the range of 80%–120% after MSPD and 15% after QuEChERS extraction. QuEChERS extraction was simpler and faster than MSPD. This methodology was applied in the analysis of 27 C. indicum samples; phorate was most frequently detected (63.0% of the sample).

中文翻译：

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预处理对菊花中37种农药残留检测的影响

本研究旨在建立一种气相色谱-质谱联用检测菊花（C. indicum）中37 种农药的方法。) 并研究基质诱导增强效应的降低。比较了 QuEChERS 萃取和基质固相分散 (MSPD) 对回收率和基质效应 (ME) 的影响。萃取和基质固相分散 (MSPD) 对回收率和基质效应 (ME) 进行了比较以降低 ME。对净化吸附剂、溶剂的体积和类型以及处理时间进行了优化。确定了准确度（作为回收率）、精密度（作为相对标准偏差，RSD）、线性、定量限和检测限。对于 MSPD 和 QuEChERS 萃取，使用混合标准溶液的三个水平的回收率分别在 76% 和 120% 之间，RSD ≤15%，以及 76% 和 120%，RSD ≤11%。结果表明，MSPD 后 21 种农药的 ME 范围为 80%–120%，QuEChERS 提取后为 15%。QuEChERS 提取比 MSPD 更简单、更快。该方法用于分析 27C. 籼稻样品；甲拌磷是最常检测到的（占样本的 63.0%）。