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Risk Factors for Sudden Infant Death in North Carolina
Frontiers in Pediatrics ( IF 2.1 ) Pub Date : 2021-12-10 , DOI: 10.3389/fped.2021.770803
Merick M Yamada 1 , Michael B Rosamilia 2 , Karen E Chiswell 2 , Alfred D'Ottavio 2 , Tracy Spears 2 , Claire Osgood 2 , Marie Lynn Miranda 3 , Nina Forestieri 4 , Jennifer S Li 1, 2 , Andrew P Landstrom 1, 5
Affiliation  

Background: Sudden infant death syndrome (SIDS) is the sudden, unexplained death of infants <1 year old. SIDS remains a leading cause of death in US infants. We aim to identify associations between SIDS and race/ethnicity, birth weight/gestational age, and socioeconomic/environmental factors in North Carolina (NC) to help identify infants at risk for SIDS.

Methods and Results: In this IRB-approved study, infant mortality 2007–2016 and death certificate-linked natality 2007–2014 were obtained from the NC Department of Health and Human Services. General, NC natality statistics 2007–2016 were obtained from CDC Wonder. Association between SIDS/total infant death and covariates (below) were calculated. Total infant mortality decreased 2007–2016 by an average of 14 deaths/100,000 live births per year, while SIDS incidence remained constant. Risk ratios of SIDS/total infant deaths, standardized to Non-Hispanic White, were 1.76/2.41 for Non-Hispanic Black and 0.49/0.97 for Hispanic infants. Increased SIDS risk was significantly and independently associated with male infant sex, Non-Hispanic Black maternal race/ethnicity, young maternal age, low prenatal care, gestational age <39 weeks, birthweight <2500 g, low maternal education, and maternal tobacco use (p < 0.01). Maternal previous children now deceased also trended toward association with increased SIDS risk.

Conclusions: A thorough SIDS risk assessment should include maternal, socioeconomic, and environmental risk factors as these are associated with SIDS in our population.

更新日期:2021-12-10
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