Seminars in Ophthalmology ( IF 1.7 ) Pub Date : 2021-12-07 , DOI: 10.1080/08820538.2021.2000623 Noraliz García-O'Farrill 1, 2 , Sangeethabalasri Pugazhendhi 1, 3 , Peter A Karth 1 , Allan A Hunter 1
ABSTRACT
Background
Radiation retinopathy is a chronic, progressive, vision-threatening complication from exposure to various radiation sources. While several treatment modalities are available, proper management for this disease is a continuing challenge with no consensus on the most efficacious.
Objective
The aim of this article is to provide an updated review of the published literature on the course of the disease, available treatments and their efficacies, frequency of regimen, core issues in patient management, and additional newer treatment modalities, including possible prophylactic approaches.
Value
We also highlighted the challenges encountered with managing chronically treated patients through an analysis of a clinical case report on a patient who was treated for several years with different modalities after a diagnosis of radiation retinopathy.
中文翻译:
放射性视网膜病变的复杂性和管理进展
摘要
背景
放射性视网膜病变是一种慢性、进行性、威胁视力的并发症,因暴露于各种辐射源。虽然有几种治疗方式可供选择,但对这种疾病的适当管理是一个持续的挑战,没有就最有效的方式达成共识。
客观的
本文的目的是对已发表的有关疾病病程、可用治疗及其疗效、治疗频率、患者管理的核心问题以及其他更新的治疗方式(包括可能的预防方法)的文献进行更新回顾。
价值
我们还通过分析一名患者的临床病例报告,强调了在管理长期治疗的患者方面遇到的挑战,该患者在诊断出放射性视网膜病变后接受了几年的不同方式的治疗。