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Teaching NeuroImage: Seizures as the Initial Symptom of Relapsing Polychondritis
Neurology ( IF 7.7 ) Pub Date : 2022-02-08 , DOI: 10.1212/wnl.0000000000013144
Yingying Xu 1 , Yujie Meng 1 , Ping Wang 1 , Lin Sun 1 , Shunliang Xu 1
Affiliation  

A 41-year-old man presented with generalized tonic-clonic seizures. MRI revealed left subinsular and right frontal cortex lesions (Figure 1). CSF analysis showed 17 white cells/mm3 (lymphocytes 92%), normal protein, and glucose. The infection and autoimmune screening were negative. On day 3, bilateral auricles swelling and episcleritis emerged (Figure 2). Biopsy of left auricle revealed perivascular lymphocytic infiltration (Figure 2), consistent with relapsing polychondritis (RP). The patient's symptoms improved after oral prednisolone.



中文翻译:

NeuroImage 教学:癫痫发作是复发性多软骨炎的最初症状

一名 41 岁男性出现全身强直阵挛发作。MRI 显示左侧岛下和右侧额叶皮层病变(图 1)。CSF 分析显示 17 个白细胞/mm 3(淋巴细胞 92%)、正常蛋白质和葡萄糖。感染和自身免疫筛查均为阴性。第 3 天,出现双侧耳廓肿胀和巩膜外层炎(图 2)。左耳廓活检显示血管周围淋巴细胞浸润(图 2),与复发性多软骨炎 (RP) 一致。口服泼尼松龙后,患者的症状有所改善。

更新日期:2022-02-09
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