ABSTRACT

Clinical burnout has been associated with impaired cognitive functioning; however, inconsistent findings have been reported regarding the pattern and magnitude of cognitive deficits. The aim of this systematic review and multivariate meta-analysis was to assess cognitive function in clinical burnout as compared to healthy controls and identify the pattern and severity of cognitive dysfunction across cognitive domains. We identified 17 studies encompassing 730 patients with clinical burnout and 649 healthy controls. Clinical burnout was associated with impaired performance in episodic memory (g = −0.36, 95% CI −0.57 to −0.15), short-term and working memory (g = −0.36, 95% CI −0.52 to −0.20), executive function (g = −0.39, 95% CI −0.55 to −0.23), attention and processing speed (g = −0.43, 95% CI −0.57 to −0.29) and fluency (g = −0.53, 95% CI −1.04 to −0.03). There were no differences between patients and controls in crystallized (k = 6 studies) and visuospatial abilities (k = 4). Our findings suggest that clinical burnout is associated with cognitive impairment across multiple cognitive domains. Cognitive dysfunction needs to be considered in the clinical and occupational health management of burnout to optimise rehabilitation and support return-to-work.

摘要

临床倦怠与认知功能受损有关。然而，关于认知缺陷的模式和严重程度的报告结果不一致。本系统评价和多变量荟萃分析的目的是评估与健康对照相比临床倦怠的认知功能，并确定跨认知领域的认知功能障碍的模式和严重程度。我们确定了 17 项研究，包括 730 名临床倦怠患者和 649 名健康对照者。临床倦怠与情景记忆（g  = -0.36, 95% CI -0.57 to -0.15）、短期和工作记忆（g  = -0.36, 95% CI -0.52 to -0.20）、执行功能受损有关（克 = -0.39, 95% CI -0.55 to -0.23), 注意力和处理速度 ( g  = -0.43, 95% CI -0.57 to -0.29) 和流畅度 ( g  = -0.53, 95% CI -1.04 to -0.03) . 在结晶（k  = 6 项研究）和视觉空间能力（k  = 4）方面，患者和对照组之间没有差异。我们的研究结果表明，临床倦怠与跨多个认知领域的认知障碍有关。在职业倦怠的临床和职业健康管理中需要考虑认知功能障碍，以优化康复并支持重返工作岗位。