Purpose

To describe clinical characteristics and visual outcomes of non-traumatic open globe injuries.

Setting

A level 1 trauma centre in a large urban medical centre.

Design

Retrospective study.

Methods

Charts of non-traumatic open globe patients admitted to MHH-TMC from 1/2010 to 3/2015 were reviewed for demographics, cause, clinical characteristics, visual acuity (VA) and enucleation.

Results

Thirty eyes were included: 15 (50%) were males with a mean age of 47 (±28) years. All presented with zone 1 injury. Twenty-five (83%) had a perforated corneal ulcer. Presenting VA was count fingers (n = 3, 10%) to NLP (n = 6, 20%). Twenty-four (80%) involved infection, 5 (17%) congenital, 3 (10%) chemical burn and 2 (7%) neurotrophic. Conjunctival injection (n = 22, 77%), corneal opacification (n = 20, 71%) and relative afferent pupillary defect (n = 9, 44%) were common. After treatment, 23 (88%) were worse than 6/60 (20/200), 9 (35%) were NLP and 8 (27%) required enucleation.

Conclusions

Often non-traumatic open globe injuries are zone 1 and due to perforated infectious ulcers. Compared to previously reported traumatic injuries, these have higher rates of enucleation (27% vs 8%) and poorer final VA (88% vs 68% worse than 6/60 20/200).

中文翻译：

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非创伤性开放性眼球损伤：呈现特征和视觉结果

 目的

描述非创伤性开放性眼球损伤的临床特征和视觉结果。

 环境

大型城市医疗中心内的 1 级创伤中心。

 设计

 回顾性研究。

 方法

对 2010 年 1 月 1 日至 2015 年 3 月入住 MHH-TMC 的非创伤性开放性眼球患者的人口统计、病因、临床特征、视力 (VA) 和摘除情况进行了回顾。

 结果

纳入 30 只眼睛：15 只 (50%) 为男性，平均年龄为 47 (±28) 岁。所有患者均出现 1 区损伤。二十五人 (83%) 患有穿孔角膜溃疡。呈现 VA 是数手指（ n = 3, 10%) 到 NLP ( n = 6, 20%）。 24 例 (80%) 涉及感染，5 例 (17%) 先天性，3 例 (10%) 化学烧伤，2 例 (7%) 神经营养性烧伤。结膜注射（ n = 22, 77%), 角膜混浊 ( n = 20, 71%) 和相对传入瞳孔缺陷 ( n = 9, 44%) 很常见。治疗后，23例（88%）比6/60（20/200）更差，9例（35%）进行NLP，8例（27%）需要摘除。

 结论

通常，非外伤性开放性眼球损伤属于 1 区，是由穿孔的感染性溃疡引起的。与之前报道的外伤相比，这些损伤的摘除率较高（27% vs 8%），最终视力较差（88% vs 68% 比 6/60 20/200 差）。