The emerging method MicroED was used in combination with NMR spectroscopy to elucidate the structures of eight novel and unusual alkaloids produced by the marine bacterial symbiont Phaeobacter inhibens when it is challenged with algal metabolites. Four of these molecules exhibited algaecidal activity, indicating that the bacteria can combine algal precursors to produce complex, hybrid natural products that kill the algal host.

中文翻译：

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通过 NMR 光谱和 MicroED 对海洋藻类-细菌共生体中隐性除藻剂的结构解析

新兴的方法 MicroED 与 NMR 光谱结合使用，以阐明海洋细菌共生体Phaeobacter inhibens在受到藻类代谢物挑战时产生的八种新的和不寻常的生物碱的结构。其中四种分子表现出杀藻活性，表明细菌可以结合藻类前体产生复杂的混合天然产物，从而杀死藻类宿主。