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A Tale of Two Histologies: Dissecting the Biology of Lineage Transformation in Lung Cancer
Cancer Discovery ( IF 29.7 ) Pub Date : 2021-12-01 , DOI: 10.1158/2159-8290.cd-21-1222
Catherine B Meador 1 , Christine M Lovly 2
Affiliation  

Summary: Lineage plasticity is an important, and likely underappreciated, mechanism of treatment resistance in lung cancer. Here, Quintanal-Villalonga and colleagues integrate results from multiomic analyses to provide key new insights into the biology of lineage plasticity. See related article by Quintanal-Villalonga et al., [p. 3028][1] . [1]: /lookup/volpage/11/3028?iss=12

中文翻译:

两种组织学的故事:剖析肺癌谱系转化的生物学

总结:谱系可塑性是肺癌治疗耐药性的一个重要但可能被低估的机制。在这里,Quintal-Villalonga 及其同事整合了多组学分析的结果,为谱系可塑性生物学提供了重要的新见解。参见 Quintanal-Villalonga 等人的相关文章,[p. 3028][1]。[1]:/lookup/volpage/11/3028?iss=12
更新日期:2021-12-02
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