ABSTRACT

Purpose

Describe presumed microbial keratitis cases resulting in evisceration/enucleation from 2012 to 2016 in Sydney, Australia

Methods

A retrospective case review included 33 patients. Cases were identified from pathology and hospital coding data. Sociodemographic and clinical details were collated.

Results

Mean age was 79 years (range: 38–100 years), and 64% female. There were 30 eviscerations and 3 enucleations, at a median time of 8 days (range: 1–270 days) due to endophthalmitis (n = 15, 45%). Major ocular associated factors included topical corticosteroid use in 12 patients (36%), exposure keratopathy in 4 (12%), ectropion in 3 (9%), degenerative corneal disease in 3 (9%), and corneal graft in 2 (6%). Pseudomonas aeruginosa was the most common isolate with no reports of antimicrobial resistance.

Conclusions

Educating elderly patients with a history of topical corticosteroid use, corneal or ocular surface disease about prompt hospital presentation and treatment of microbial keratitis may decrease the probability of losing the eye.

中文翻译：

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导致澳大利亚悉尼内脏摘除的疑似微生物性角膜炎病例

摘要

目的

描述 2012 年至 2016 年澳大利亚悉尼导致内脏摘除/去核的假定微生物性角膜炎病例

方法

回顾性病例回顾包括 33 名患者。病例是根据病理学和医院编码数据确定的。整理了社会人口学和临床细节。

结果

平均年龄为 79 岁（范围：38-100 岁），女性占 64%。由于眼内炎 ( n = 15, 45%)，中位时间为 8 天（范围：1-270 天），发生 30 次内脏切除和 3 次眼球摘除。主要眼部相关因素包括 12 名患者 (36%) 使用局部皮质类固醇，4 名 (12%) 患者暴露角膜病变，3 名 (9%) 患者外翻，3 名 (9%) 患者角膜退化性疾病，2 名患者 (6%) 角膜移植%)。铜绿假单胞菌是最常见的分离菌，没有抗菌素耐药性的报告。

结论

对有局部皮质类固醇使用史、角膜或眼表疾病的老年患者进行及时就诊和微生物性角膜炎治疗的教育，可能会降低失明的可能性。