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Aortic stenosis management in 2021: better teaming up than fighting between specialties
European Heart Journal ( IF 37.6 ) Pub Date : 2021-11-28 , DOI: 10.1093/eurheartj/ehab778
Helmut Baumgartner 1
Affiliation  

Graphical Abstract
Graphical AbstractManagement of severe symptomatic aortic stenosis over the decades. Left upper panel: 1980–1990. Valve replacement reverses the dismal outcome of severe symptomatic AS (adapted from Horstkotte and Loogen3). Right upper panel: 1990–2000. Many patients do not receive AVR because of older age and comorbidities (graph based on data from Charlson et al.,5 Iung et al.,6 and Bouma et al.7). Left lower panel: 2000–2010. TAVI evolves as an alternative to SAVR, RCTs demonstrate non-inferiority (adapted from Jorgensen et al.13 and Makkar et al.14). Right lower panel: 2010–2020. The number of AVRs more than doubles and in-hospital mortality decreases for SAVR and TAVI. AS, aortic stenosis; AVR, aortic valve replacement; RCT, randomized controlled trial; TAVI, transcatheter aortic valve implantation; TAVR, transcatheter aortic valve replacement.


中文翻译:

2021年的主动脉瓣狭窄管理:比专业之间的斗争更好的合作

图形概要
几十年来严重症状性主动脉瓣狭窄的图形摘要管理。左上图:1980–1990。瓣膜置换可逆转严重症状性 AS 的惨淡结局(改编自 Horstkotte 和 Loogen 3)。右上图:1990–2000。由于年龄较大和合并症,许多患者未接受 AVR(图表基于 Charlson等人5 Iung6Bouma等人7数据)。左下图:2000–2010。TAVI 演变为 SAVR 的替代方案,RCT 证明了非劣效性(改编自 Jorgensen等人13Makkar14)。右下面板:2010–2020。SAVR 和 TAVI 的 AVR 数量增加了一倍多,院内死亡率降低。AS,主动脉瓣狭窄;AVR,主动脉瓣置换术;RCT,随机对照试验;TAVI,经导管主动脉瓣植入术;TAVR,经导管主动脉瓣置换术。
更新日期:2021-11-28
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