Background. Noninvasive assessment of metabolic processes that sustain regeneration of human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics and to accelerate development of new treatments to counter retinal diseases. Fluorescent vitamin A derivatives, which are the chemical intermediates of these processes, are highly sensitive to UV light; thus, safe analyses of these processes in humans are currently beyond the reach of even the most modern ocular imaging modalities.

中文翻译：

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使用 2 光子激发荧光扫描激光检眼镜对人眼进行体内成像

背景。对维持人类视网膜视觉色素（视觉周期）再生的代谢过程进行非侵入性评估对于改善眼科诊断和加速开发新的治疗方法以对抗视网膜疾病至关重要。荧光维生素 A 衍生物是这些过程的化学中间体，对紫外线高度敏感；因此，即使是最现代的眼部成像方式，目前也无法对人类这些过程进行安全分析。