NT-proBNP as a marker for atrial fibrillation and heart failure in four observational outpatient trials,ESC Heart Failure

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NT-proBNP as a marker for atrial fibrillation and heart failure in four observational outpatient trials
ESC Heart Failure ( IF 3.2 ) Pub Date : 2021-11-30 , DOI: 10.1002/ehf2.13703
Stefanie M Werhahn _{1,

2} , Christian Becker ₁ , Meinhard Mende ₃ , Helge Haarmann ₁ , Kathleen Nolte ₁ , Ulrich Laufs ₄ , Samira Zeynalova _{3,

5} , Markus Löffler _{3,

5} , Nikolaos Dagres ₆ , Daniela Husser ₆ , Marcus Dörr _{7,

8} , Stefan Gross _{7,

8} , Stephan B Felix _{7,

8} , Astrid Petersmann ₉ , Christoph Herrmann-Lingen _{2,

10} , Lutz Binder _{2,

11} , Martin Scherer ₁₂ , Gerd Hasenfuß _{1,

2} , Burkert Pieske _{13,

14,

15} , Frank Edelmann _{1,

2,

13,

14} , Rolf Wachter _{1,

2,

4}

Affiliation

Clinic for Cardiology and Pneumology, University Medical Center Göttingen, Göttingen, Germany.
German Centre for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany.
Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University Hospital Leipzig, Leipzig, Germany.
Department of Cardiology, University Hospital, Leipzig University, Leipzig, Germany.
LIFE Research Center for Civilization Diseases, Leipzig, Germany.
Department of Electrophysiology, Heart Center, Leipzig, Germany.
Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Department of Psychosomatic Medicine and Psychotherapy, University of Oldenburg Medical Centre, Oldenburg, Germany.
Institute for Clinical Chemistry/UMG-Laboratories, University Medical Center Göttingen, Göttingen, Germany.
Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Department of Cardiology, Charité University Medicine, Campus Virchow Klinikum, Berlin, Germany.
German Centre for Cardiovascular Research (DZHK), partner site Berlin, Berlin, Germany.
German Heart Center, Berlin, Germany.

Heart failure (HF) and atrial fibrillation (AF) frequently coexist and are both associated with increased levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP). It is known that AF impairs the diagnostic accuracy of NT-proBNP for HF. The aim of the present study was to compare the diagnostic and predictive accuracy of NT-proBNP for HF and AF in stable outpatients with cardiovascular risk factors.

中文翻译：

四项观察性门诊试验中 NT-proBNP 作为心房颤动和心力衰竭的标志物

心力衰竭 (HF) 和心房颤动 (AF) 经常共存，并且都与 N 末端 B 型利钠肽原 (NT-proBNP) 水平升高相关。已知 AF 会损害 NT-proBNP 对 HF 的诊断准确性。本研究的目的是比较 NT-proBNP 对具有心血管危险因素的稳定门诊患者心力衰竭和房颤的诊断和预测准确性。

更新日期：2021-11-30

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