In this study, we reported Shiga toxin-producing Escherichia coli (STEC) in 847 samples, including those in coastal waters, sediments, and fish samples in the Southeast Coast of India. A total of 3742 E. coli strains were identified using conventional and molecular identification methods. Of these, 1518 isolates expressed virulent genes Stx1, Stx2, and Eae; effects on these genes on toxicity were examined. Furthermore, 2224 non-STEC isolates caused hemolytic uremic syndrome and played a key role in the persistence of STEC contamination. We conclude that toxin production is not adequate to cause disease, and the pathogenic mechanism of STEC remains poorly defined. Therefore, the present study indicates the status of pollution, highlighting the need for sanitation in public health.

在这项研究中，我们在 847 个样本中报告了产志贺毒素大肠杆菌(STEC)，其中包括印度东南海岸沿海水域、沉积物和鱼类样本中的样本。使用常规和分子鉴定方法共鉴定出3742株大肠杆菌菌株。其中，1518 个分离株表达毒力基因Stx1、Stx2和Eae; 检查了这些基因对毒性的影响。此外，2224 个非 STEC 分离株引起溶血性尿毒症综合征，并在 STEC 污染的持续存在中发挥了关键作用。我们得出结论，毒素的产生不足以引起疾病，STEC 的致病机制仍然不明确。因此，本研究表明了污染状况，强调了公共卫生对卫生的需求。