PURPOSE

To characterize the features of hydrophilic intraocular lenses (IOLs) important in the clinical context of expected prolonged duration time of the IOL within the eye.

DESIGN

Perspective.

METHODS

Discussion includes possible factors and mechanisms associated with hydrophilic IOLs’ susceptibility to calcification and posterior capsule opacification (PCO) formation.

RESULTS

Results of recently reported studies show that particular surgeries, such as pars plana vitrectomy, Descemet stripping (automated) endothelial keratoplasty, and Descemet membrane endothelial keratoplasty with intraocular gas or air injection, might predispose the calcification process of hydrophilic IOLs, leading to a significant decrease in visual quality and possibly explantation of the IOL. Hydrophilic IOLs are more susceptible than hydrophobic IOLs to PCO formation, which is the most common of late postoperative complications that are associated with significant side effects.

CONCLUSIONS

We believe that all patients should be informed about the higher risk of calcification and PCO associated with hydrophilic IOLs. We also recommend limiting the use of hydrophilic acrylic IOLs during cataract surgery, especially when it is combined with pars plana vitrectomy or endothelial keratoplasty, and in patients with endothelial diseases who will probably require operation on it in the future.

中文翻译：

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我们应该放弃亲水性人工晶状体吗？

目的

表征亲水性人工晶状体 (IOL) 的特征，在预期眼内 IOL 持续时间延长的临床背景下很重要。

设计

看法。

方法

讨论包括与亲水性 IOL 对钙化和后囊混浊 (PCO) 形成的敏感性相关的可能因素和机制。

结果

最近报道的研究结果表明，特定的手术，如玻璃体切除术、后弹力层剥离（自动）内皮角膜移植术和眼内气体或空气注射的后弹力膜内皮角膜移植术，可能会导致亲水性 IOL 的钙化过程，导致显着减少在视觉质量和 IOL 的可能解释方面。亲水性人工晶状体比疏水性人工晶状体更容易形成 PCO，这是最常见的术后晚期并发症，并伴有明显的副作用。

结论

我们认为，应告知所有患者与亲水性人工晶状体相关的钙化和 PCO 较高风险。我们还建议在白内障手术期间限制使用亲水性丙烯酸人工晶状体，特别是当它与平坦部玻璃体切除术或内皮角膜移植术相结合时，以及未来可能需要对其进行手术的内皮疾病患者。