Mobilization of trapped ganglia is of fundamental importance in two-phase displacement. Wettability alteration could be an effective approach to mobilizing ganglia, yet its feasibility as well as the impact of wettability in general lacks study. We investigate the wettability effects on trapped ganglia by theoretical analysis and numerical simulations for both fixed and altering wettability. For fixed wettability, it is found out that the critical pressure to mobilize trapped ganglia is symmetric about and usually peaks at the neutrally wet conditions (for simplicity, the invading and defending fluid are referred to as water and oil), but mobilized ganglia favor more water-wet conditions to be further displaced. This is due to the difference in the evolvement of ganglia after initial mobilization under different wetting conditions: water-wetness contributes to the cooperative advancing of multiple interfaces, making ganglia continue moving as a whole, while oil-wetness leads to Haines jump in a single throat, which easily breaks up ganglia into smaller ones and leaves them trapped again. For altering wettability from oil-wet to water-wet through the transport of certain solute, we for the first time identify two crucial factors for the mobilization of ganglia. First, only the heterogeneous wetting state during the dynamic altering process enables the initial mobilization, whereas a step-wise alteration has little effect. Second, ganglia have to be able to merge with one another during the time window of the altering process for further displacement. Otherwise, an isolated trapped ganglion can only have limited mobilization at first by wettability alteration, and gets trapped again when the alteration is complete.

被困神经节的动员在两相位移中至关重要。润湿性改变可能是调动神经节的有效方法，但其可行性以及润湿性的影响通常缺乏研究。我们通过固定和改变润湿性的理论分析和数值模拟研究了对被困神经节的润湿性影响。对于固定润湿性，发现动员被困神经节的临界压力是对称的，通常在中性湿润条件下达到峰值（为简单起见，入侵和防御流体被称为水和油），但动员的神经节更有利于水湿条件将被进一步取代。这是由于在不同润湿条件下初始动员后神经节的演变存在差异：水湿有助于多个界面的协同推进，使神经节作为一个整体继续运动，而油湿性导致海恩斯在一个喉咙里跳跃，很容易将神经节分解成更小的神经节，让它们再次陷入困境。为了通过某些溶质的运输将润湿性从油湿性变为水湿性，我们首次确定了神经节动员的两个关键因素。首先，只有动态改变过程中的异质润湿状态才能进行初始动员，而逐步改变几乎没有影响。其次，神经节必须能够在改变过程的时间窗口内相互融合以进一步移位。否则，一个孤立的被困神经节最初只能通过润湿性改变进行有限的活动，