Chronic kidney disease (CKD) has a complicated relationship with the heart, leading to many adverse outcomes. The aim of this study was to evaluate the relationship between CKD and the incidence of atrial fibrillation (AF) and heart failure (HF) along with mortality as a competing risk in general population cohorts. We also included an assessment of baseline biomarkers of inflammation, myocardial injury, and left ventricular dysfunction with risk of AF and HF, respectively, to shed light on the potential underlying pathophysiology.

中文翻译：

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基于一般人群的慢性肾病和心房颤动和心力衰竭的风险：BiomarCaRE 项目

慢性肾脏病 (CKD) 与心脏的关系复杂，导致许多不良后果。本研究的目的是评估 CKD 与心房颤动 (AF) 和心力衰竭 (HF) 的发病率之间的关系，以及死亡率作为一般人群队列中的竞争风险。我们还分别评估了炎症、心肌损伤和左心室功能障碍的基线生物标志物以及 AF 和 HF 的风险，以阐明潜在的潜在病理生理学。