Background

People with hand osteoarthritis (OA) may benefit from resistance training interventions. To date the feasibility of a such interventions for symptomatic hand OA, as per international guidelines, is unknown.

Objective

Determine the feasibility of a clinical trial comparing resistance training to an advice only control group in people with symptomatic hand OA.

Design

Single-blind, randomised, controlled feasibility study.

Methods

The American College of Rheumatology criteria for hand OA were utilised for inclusion. Participants were randomly allocated (1:1:1) to advice and blood flow restriction training (BFRT), advice and traditional high intensity training (HIT), or advice only (control). Participants receiving BFRT and HIT underwent supervised hand exercises three times a week for six weeks. Feasibility measures included recruitment rate, adherence, exercise induced pain, training acceptability, pain flares, and adverse events. Number of treatment responders, pain, grip strength, and hand function were also recorded.

Results

In total, 191 participants were screened, 59 (31%) were included. Retention rate was 89% for BFRT and 79% for HIT. Exercise did not worsen pain following training sessions, and training acceptability was equal between groups. Pain flares occurred in 1.6% (BFRT) and 4% (HIT) out of all the training sessions. There was one adverse event in the HIT group, with the participants withdrawing from the study due to pain. The number of treatment responders, and improvements in pain, were greater with BFRT and HIT. Grip and function did not improve.

Conclusion

A clinical trial comparing resistance training to advice for people with symptomatic hand OA is feasible.

中文翻译：

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六周的阻力训练（加上建议）与仅针对手部骨关节炎的建议：一项单盲、随机、可控的可行性试验

背景

手部骨关节炎 (OA) 患者可能会从阻力训练干预中受益。迄今为止，根据国际指南，对症状性手部 OA 进行此类干预的可行性尚不清楚。

客观的

确定在有症状的手部 OA 患者中比较阻力训练与仅建议对照组的临床试验的可行性。

设计

单盲、随机、可控的可行性研究。

方法

美国风湿病学会手部 OA 标准被用于纳入。参与者被随机分配 (1:1:1) 到建议和血流限制训练 (BFRT)、建议和传统高强度训练 (HIT) 或仅建议（控制）。接受 BFRT 和 HIT 的参与者每周进行 3 次监督手部练习，持续 6 周。可行性措施包括招募率、依从性、运动诱发的疼痛、训练可接受性、疼痛发作和不良事件。还记录了治疗反应者的数量、疼痛、握力和手部功能。

结果

总共筛选了 191 名参与者，其中包括 59 名 (31%)。BFRT 的保留率为 89%，HIT 的保留率为 79%。训练后锻炼并没有加重疼痛，并且各组之间的训练可接受性相同。在所有训练课程中，有 1.6% (BFRT) 和 4% (HIT) 出现疼痛发作。HIT 组发生了一起不良事件，参与者因疼痛退出研究。BFRT 和 HIT 治疗反应者的数量和疼痛的改善更大。抓地力和功能没有改善。

结论

一项将阻力训练与对有症状的手部 OA 患者的建议进行比较的临床试验是可行的。