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Discovery of tumor immune infiltration-related snoRNAs for predicting tumor immune microenvironment status and prognosis in lung adenocarcinoma
Computational and Structural Biotechnology Journal ( IF 4.4 ) Pub Date : 2021-11-25 , DOI: 10.1016/j.csbj.2021.11.032 Rongjun Wan 1, 2, 3, 4, 5 , Lu Bai 1, 2, 3, 4, 5 , Changjing Cai 5 , Wang Ya 1, 2, 3, 4, 5 , Juan Jiang 1, 2, 3, 4, 5 , Chengping Hu 1, 2, 3, 4, 5 , Qiong Chen 1, 2, 3, 4, 5 , Bingrong Zhao 1, 2, 3, 4, 5 , Yuanyuan Li 1, 2, 3, 4, 5
Computational and Structural Biotechnology Journal ( IF 4.4 ) Pub Date : 2021-11-25 , DOI: 10.1016/j.csbj.2021.11.032 Rongjun Wan 1, 2, 3, 4, 5 , Lu Bai 1, 2, 3, 4, 5 , Changjing Cai 5 , Wang Ya 1, 2, 3, 4, 5 , Juan Jiang 1, 2, 3, 4, 5 , Chengping Hu 1, 2, 3, 4, 5 , Qiong Chen 1, 2, 3, 4, 5 , Bingrong Zhao 1, 2, 3, 4, 5 , Yuanyuan Li 1, 2, 3, 4, 5
Affiliation
Lung adenocarcinoma (LUAD) has a high mortality rate and is difficult to diagnose and treat in its early stage. Previous studies have demonstrated that small nucleolar RNAs (snoRNAs) play a critical role in tumor immune infiltration and the development of a variety of solid tumors. However, there have been no studies on the correlation between tumor-infiltrating immune-related snoRNAs (TIISRs) and LUAD.
中文翻译:
发现肿瘤免疫浸润相关的 snoRNA 用于预测肺腺癌肿瘤免疫微环境状态和预后
肺腺癌(LUAD)死亡率高,早期诊断和治疗困难。此前的研究表明,小核仁RNA(snoRNA)在肿瘤免疫浸润和多种实体瘤的发生发展中发挥着关键作用。然而,目前尚无肿瘤浸润免疫相关snoRNA(TIISR)与LUAD之间相关性的研究。
更新日期:2021-11-25
中文翻译:
发现肿瘤免疫浸润相关的 snoRNA 用于预测肺腺癌肿瘤免疫微环境状态和预后
肺腺癌(LUAD)死亡率高,早期诊断和治疗困难。此前的研究表明,小核仁RNA(snoRNA)在肿瘤免疫浸润和多种实体瘤的发生发展中发挥着关键作用。然而,目前尚无肿瘤浸润免疫相关snoRNA(TIISR)与LUAD之间相关性的研究。