In Reply We appreciate the interest by Roberts et al in our article¹ reporting a weak association between quantitative increases in total retinal thickness, a sensitive and objective measure of optic disc edema, and lateral ventricle volume after spaceflight. We found that changes in lateral ventricle volume do not provide strong predictive power for the development of optic disc edema during spaceflight, suggesting additional contributing factors associated with the weightless environment influence the optic nerve head and retina.

中文翻译：

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颅内隔室在航天相关神经眼综合征发展中的重要性—回复

作为回复，我们感谢 Roberts 等人在我们的第¹篇文章中报告了视网膜总厚度的定量增加、视盘水肿的敏感和客观测量以及太空飞行后侧脑室体积之间的弱关联。我们发现侧脑室体积的变化不能为太空飞行期间视盘水肿的发展提供强大的预测能力，这表明与失重环境相关的其他促成因素会影响视神经乳头和视网膜。