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Looking for the neural basis of memory
Trends in Cognitive Sciences ( IF 19.9 ) Pub Date : 2021-11-23 , DOI: 10.1016/j.tics.2021.10.010
James E Kragel 1 , Joel L Voss 1
Affiliation  

Memory neuroscientists often measure neural activity during task trials designed to recruit specific memory processes. Behavior is championed as crucial for deciphering brain–memory linkages but is impoverished in typical experiments that rely on summary judgments. We criticize this approach as being blind to the multiple cognitive, neural, and behavioral processes that occur rapidly within a trial to support memory. Instead, time-resolved behaviors such as eye movements occur at the speed of cognition and neural activity. We highlight successes using eye-movement tracking with in vivo electrophysiology to link rapid hippocampal oscillations to encoding and retrieval processes that interact over hundreds of milliseconds. This approach will improve research on the neural basis of memory because it pinpoints discrete moments of brain–behavior–cognition correspondence.



中文翻译:

寻找记忆的神经基础

记忆神经科学家经常在旨在招募特定记忆过程的任务试验中测量神经活动。行为被认为是破译大脑-记忆联系的关键,但在依赖总结判断的典型实验中却很贫乏。我们批评这种方法对在支持记忆的试验中迅速发生的多种认知、神经和行为过程视而不见。相反,眼球运动等时间分辨行为以认知和神经活动的速度发生。我们强调在体内使用眼动追踪的成功电生理学将快速海马体振荡与相互作用超过数百毫秒的编码和检索过程联系起来。这种方法将改进对记忆的神经基础的研究,因为它精确定位了大脑-行为-认知对应的离散时刻。

更新日期:2021-12-15
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