Studies on the interaction of lipid monolayer with bilayer structures, such as vesicles, are relatively scarce in the literature. In order to ascertain whether these structures interact for cationic dioctadecyldimethylammonium bromide (DODAB) monolayers at the aqueous surfaces of 0, 0.05, and 0.5 mmol L⁻¹ DODAB vesicle dispersions, differential scanning calorimetry (DSC) and surface film balance experiments were carried out. DSC results confirmed the presence of unilamellar vesicles in the subphase, while changes in the monolayer surface pressure–area per molecule (π–A) isotherm profile yielded by the presence of DODAB vesicle in the subphase revealed monolayer-vesicle interactions as a result of monomer exchanges between the monolayer and the vesicles with stronger effects at the higher vesicle concentration investigated.

中文翻译：

---

亚相中双十八烷基二甲基溴化铵单层与囊泡之间的脂质交换

关于脂质单层与双层结构（如囊泡）相互作用的研究在文献中相对较少。为了确定这些结构是否与 0、0.05 和 0.5 mmol L ^-1 DODAB 囊泡分散体的水表面上的阳离子双十八烷基二甲基溴化铵 (DODAB) 单层相互作用，进行了差示扫描量热法 (DSC) 和表面膜平衡实验。DSC 结果证实亚相中存在单层囊泡，而单层表面压力 - 每个分子的面积 ( π - A) 亚相中存在 DODAB 囊泡产生的等温线曲线显示单层-囊泡相互作用是由于单层和囊泡之间的单体交换，在所研究的较高囊泡浓度下具有更强的影响。