Background: Sulfonamides are the anti-bacterial and anti-inflammatory drugs synthesized, which are widely used as medical and veterinary antibiotics. However, the excess dosage of sulfonamides can harm human health. Drug residues in animal products also can harm human health through the food chain. The long-term consumption of animal food containing drug residues will cause some toxicity and side effects on human body functions, which will seriously threaten human health.

Methods: Electroanalytical methods are attracting much attention because of their advantage over conventional methods, as they are quick, low-cost, high sensitivity, and portable. This review examines the progress made in the selective electrochemical determination of sulfonamides in the last 20 years.

Results: In this review, we describe the development of electrochemical methods for sulfonamides determination. Then, we pay special attention to the detection of sulfonamides using molecular imprinting technology. The linear detection range with the limit of detection has been listed for comparison.

Conclusion: Electrochemical determination of sulfonamides is a fast, simple, sensitive, and cost-effective approach. The surface modification of commercial electrodes can significantly improve the sensing performance.

背景：磺胺类药物是合成的抗菌消炎药物，广泛用作医用和兽用抗生素。然而，过量服用磺胺类药物会危害人体健康。动物产品中的药物残留也会通过食物链危害人类健康。长期食用含有药物残留的动物性食品，会对人体机能产生一定的毒副作用，严重威胁人体健康。

方法：电分析方法因其快速、低成本、高灵敏度和便携性等优于传统方法而备受关注。本综述审查了过去 20 年来在选择性电化学测定磺胺类药物方面取得的进展。

结果：在这篇综述中，我们描述了磺胺类药物测定电化学方法的发展。然后，我们特别关注使用分子印迹技术检测磺胺类药物。已列出线性检测范围与检测限进行比较。

结论：磺胺类药物的电化学测定是一种快速、简单、灵敏且经济高效的方法。商用电极的表面改性可以显着提高传感性能。