Background: Pain not only affects the quality of life of an individual but can also cause mental illness due to the lack of effective treatment for long-term pain. Analgesics refer to drugs that can partially or completely relieve pain, including non-steroidal anti-inflammatory drugs and central analgesics.

Methods: In recent years, the cross integration of electrochemical analysis technology with biochemistry, materials science, biomedicine and other disciplines has driven the vigorous development of electrochemical sensing technology in the field of life sciences. The electrochemical sensor has many advantages, such as simple equipment, good specificity, high sensitivity, economy and convenience. As a newly emerging technology, electrochemical sensing technology has been increasingly used in drug analysis.

Results: This review introduces the recent advances of the detection of analgesics using electrochemical technology. We deliberately selected three representative drugs for discussion: aspirin, ibuprofen and paracetamol.

Conclusion: Electrochemical sensing technology has the advantages of high sensitivity, a low detection limit and simple operation. However, sensors still have some technical problems, such as the existence of many interference factors in actual samples in blood drug concentration monitoring and the need to further optimize the method conditions for multi-channel detection. With the continuous advancement of research, the application of new detection methods, nanomaterials, and biomolecules has enabled electrochemical technology to make certain progress in the field of drug analysis. In particular, the emergence of new nanomaterials will greatly promote the development of electrochemical sensing technology in drug analysis. As a cutting-edge technology, electrochemical sensing technology has enormous potential application value.

背景：疼痛不仅会影响个人的生活质量，还会因长期疼痛缺乏有效治疗而导致精神疾病。镇痛药是指可以部分或完全缓解疼痛的药物，包括非甾体类抗炎药和中枢镇痛药。

方法：近年来，电化学分析技术与生物化学、材料科学、生物医学等学科的交叉融合，推动了电化学传感技术在生命科学领域的蓬勃发展。电化学传感器具有设备简单、特异性好、灵敏度高、经济方便等诸多优点。电化学传感技术作为一种新兴技术，越来越多地应用于药物分析中。

结果：这篇综述介绍了使用电化学技术检测镇痛剂的最新进展。我们特意选取了三种有代表性的药物进行讨论：阿司匹林、布洛芬和扑热息痛。

结论：电化学传感技术具有灵敏度高、检出限低、操作简单等优点。然而，传感器仍存在一些技术问题，如血药浓度监测中实际样品中存在诸多干扰因素，需要进一步优化多通道检测的方法条件等。随着研究的不断进步，新的检测方法、纳米材料和生物分子的应用，使电化学技术在药物分析领域取得了一定的进展。尤其是新型纳米材料的出现，将极大地推动电化学传感技术在药物分析中的发展。电化学传感技术作为一项前沿技术，具有巨大的潜在应用价值。