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Ionic Liquids, Microextraction Methods and Capillary Electrophoresis in Biomedical Research
Current Pharmaceutical Analysis ( IF 0.7 ) Pub Date : 2021-12-31 , DOI: 10.2174/1573412917999201116214131
Natalia Miękus 1 , Martyna Ceraficka 1 , Marta Chyła 1 , Aleksandra Durska 1 , Tomasz Bączek 1
Affiliation  

The review aims to present the importance of implementing microextraction-, capillary electrophoresis- and ionic liquid-based approaches in biomedical research. These analytical strategies could improve the biochemical diagnosis of various life-threatening diseases, aid in the search for therapeutic agents, and discover drug targets. They could be used when designing newer, safer medicinal products. All the proposed analytical approaches meet the requirements of “green chemistry”- based methods, which is relevant nowadays in view of the pollution of the Earth becoming a severe problem. The review is divided into three main sections, and biomedical examples of the application of each presented approach are discussed. It is assumed that the undoubted advantages of ionic liquid-, microextraction- and capillary electrophoresis-based methods will speed up their use in the study of various clinically important analytes from different biological fluids and tissue samples.



中文翻译:

生物医学研究中的离子液体、微萃取方法和毛细管电泳

该评论旨在介绍在生物医学研究中实施基于微萃取、毛细管电泳和离子液体方法的重要性。这些分析策略可以改进对各种威胁生命的疾病的生化诊断,帮助寻找治疗剂,并发现药物靶点。它们可用于设计更新、更安全的医药产品。所有提出的分析方法都满足基于“绿色化学”的方法的要求,鉴于地球污染成为一个严重的问题,这在当今是相关的。该评论分为三个主要部分,并讨论了每种方法应用的生物医学示例。据推测,离子液体的无可置疑的优势——

更新日期:2021-11-23
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