The influence of ischemia–reperfusion (I/R) action on pancreatic blood flow (PBF) and the development of acute pancreatitis (AP) in laboratory rats is evaluated in vivo by using the laser speckle contrast imaging (LSCI). Additionally, the optical properties in norm and under condition of AP in rats were assessed using a modified integrating sphere spectrometer and inverse Monte Carlo (IMC) software. The results of the experimental study of microcirculation of the pancreas in 82 rats in the ischemic model are presented. The data obtained confirm the fact that local ischemia and changes in the blood flow velocity of the main vessels cause and provoke acute pancreatitis.

缺血再灌注 (I/R) 作用对实验室大鼠胰腺血流 (PBF) 和急性胰腺炎 (AP) 发展的影响通过使用激光散斑对比成像 (LSCI)在体内进行评估。此外，使用改进的积分球光谱仪和逆蒙特卡罗 (IMC) 软件评估了大鼠正常和 AP 条件下的光学特性。介绍了82只大鼠缺血模型胰腺微循环的实验研究结果。获得的数据证实了一个事实，即局部缺血和主要血管血流速度的变化会导致和诱发急性胰腺炎。