PURPOSE To determine the frequency and risk factors of narrow angles in pseudoexfoliation (PXF) patients. METHODS A prospective case-control study was conducted during the period from March 2017 to December 2020. Adult patients (above 40 years) presenting with PXF were consecutively enrolled (study group). Cases were matched with individuals above 40 years presenting to a comprehensive ophthalmology clinic without evidence of PXF (control group). RESULTS We enrolled 196 PXF patients and 98 controls. The occurrence of narrow angles was 25% in the PXF group and 5.1% in the control group (P = 0.0001). Compared to controls, PXF patients were older (72.6 ± 9.6 vs. 64.4 ± 8.5, P < 0.0001) and had a lower mean ACD (2.79 ± 0.4 vs. 3.05 ± 0.4, P < 0.0001). There was no difference in AL measurements between both groups (23.3 ± 1.4 vs. 23.7 ± 1.0, P = 0.0714). After stratification by age group and gender, the risk of narrow angles was higher in PXF patients above 70 years (OR, 4.15; 95% CI, 0.91-23.87; P, 0.044). There was no gender difference in the risk of developing narrow angles. CONCLUSION Narrow angles are more frequently encountered in PXF patients compared to controls. Advanced age (> 70 years) is significantly associated with an increased likelihood of developing narrow angles.

中文翻译：

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假性剥脱患者狭窄角度的频率和危险因素：病例对照研究。

目的 确定假性剥脱 (PXF) 患者发生窄角的频率和危险因素。方法 在 2017 年 3 月至 2020 年 12 月期间进行了一项前瞻性病例对照研究。连续纳入 PXF 成年患者（40 岁以上）（研究组）。病例与在综合眼科诊所就诊但没有 PXF 证据的 40 岁以上个体相匹配（对照组）。结果 我们招募了 196 名 PXF 患者和 98 名对照。PXF 组的窄角发生率为 25%，对照组为 5.1%（P = 0.0001）。与对照组相比，PXF 患者年龄较大（72.6 ± 9.6 对 64.4 ± 8.5，P < 0.0001），平均 ACD 较低（2.79 ± 0.4 对 3.05 ± 0.4，P < 0.0001）。两组之间的 AL 测量值没有差异（23.3 ± 1.4 vs. 23.7 ± 1.0，P = 0.0714）。按年龄组和性别分层后，70 岁以上 PXF 患者的窄角风险更高（OR，4.15；95% CI，0.91-23.87；P，0.044）。发展窄角的风险没有性别差异。结论 与对照组相比，PXF 患者更常遇到窄角。高龄（> 70 岁）与发生窄角的可能性增加显着相关。