Purpose: 

The purpose of the study was to appraise the methodological quality of the highest impact blepharoplasty research and to describe prevalent research themes.

Methods: 

The 100 most highly cited research papers relevant to blepharoplasty were obtained from Web of Science, with no journal or date limitations applied. Data extraction included the study design, main research topic and specialty, outcome measures, and citation count. Each paper’s level of evidence was independently evaluated by 2 authors according to the Oxford Centre for Evidence-Based Medicine system.

Results: 

Overall, the 100 most cited blepharoplasty research papers were cited by 4,194 papers. The mean number of citations for each paper was 73 (range: 42–239). Most of the papers presented level 4 (n = 51) or level 5 (n = 35) evidence, which is consistent with the predominance of case series (n = 47) and expert opinions (n = 18) amongst study designs. No papers achieved level 1 (highest) evidence. Six papers presented level 2 evidence and 8 papers presented level 3. Significant research foci included innovative surgical techniques (n = 65) and anatomical considerations (n = 10), with reconstructive and cosmetic implications. Senior authors were mainly affiliated with centers of plastic (n = 53) or ophthalmic/oculoplastic (n = 34) surgery. Only 3 papers used validated subjective or objective cosmetic outcome measures.

Conclusions: 

Despite a significant impact on current practice, the level of evidence of the highly cited blepharoplasty research was predominantly low. Robust research methodology, through well-designed studies and standardized outcome measures, is necessary to facilitate evidence synthesis and guide clinical practice.

中文翻译：

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循证眼睑成形术：对高被引研究论文的分析

目的： 

该研究的目的是评估影响最大的眼睑成形术研究的方法学质量，并描述普遍的研究主题。

方法： 

与眼睑成形术相关的 100 篇引用率最高的研究论文均来自 Web of Science，没有期刊或日期限制。数据提取包括研究设计、主要研究主题和专业、结果测量和引用计数。每篇论文的证据水平均由 2 位作者根据牛津循证医学中心系统独立评估。

结果： 

总体而言，被引用最多的 100 篇眼睑成形术研究论文被 4,194 篇论文引用。每篇论文的平均引用次数为 73 次（范围：42-239）。大多数论文提出了 4 级 (n = 51) 或 5 级 (n = 35) 证据，这与研究设计中案例系列 (n = 47) 和专家意见 (n = 18) 的优势一致。没有论文达到 1 级（最高）证据。6 篇论文提出了 2 级证据，8 篇论文提出了 3 级证据。重要的研究重点包括创新手术技术 (n = 65) 和解剖学考虑 (n = 10)，具有重建和美容方面的意义。资深作者主要隶属于整形（n = 53）或眼科/眼科（n = 34）手术中心。只有 3 篇论文使用了经过验证的主观或客观美容结果测量。

结论： 

尽管对当前实践产生了重大影响，但被高度引用的眼睑成形术研究的证据水平主要是低的。通过精心设计的研究和标准化的结果测量，稳健的研究方法对于促进证据综合和指导临床实践是必要的。