Myiasis is defined as the infestation of living tissues by Diptera larvae. Ophthalmic involvement occurs in less than 5% of cases. As the most uncommon type of involvement, orbital myiasis usually affects patients with poor personal hygiene, a low socioeconomic status, a history of surgery, and cancer. In January 2020, an 89-year-old man presented to the Oculoplastic Department of Farabi Eye Hospital (Iran) with a history of left-side progressive orbital mass for six months. A large infiltrative mass of the left orbit with extension to the globe, periorbita, and adnexa was remarkable at the presentation, and its appearance suggested malignancy. Our findings persuaded us to perform exenteration and histopathological evaluation which were reported as “undifferentiated carcinoma”. Regular follow-up visits were recommended. In June 2020, with a 3-month delay, the patient presented with the recurrence of the mass complicated with mobile alive larva. Examinations revealed numerous maggots crawling out of an ulcerative and foul-smelling lesion. He stated that fear of COVID-19 infection postponed his follow-up visit. The patient underwent immediate mechanical removal of larvae, followed by wide local excision of the mass. Patients with carcinoma of the adnexal tissues seem to be more prone to myiasis infestation even though it is an uncommon disease. Since COVID-19 is an ongoing pandemic with no end in sight appropriate protocols should be implemented to prevent loss of follow-up in these high risk patients.

中文翻译：

---

COVID-19 时代复发性未分化癌的眼眶蝇蛆病：病例报告和文献简要回顾

蝇蛆病被定义为双翅目幼虫对活组织的侵染。不到 5% 的病例发生眼部受累。作为最不常见的受累类型，眼眶蝇蛆病通常影响个人卫生差、社会经济地位低、有手术史和癌症的患者。2020 年 1 月，一名 89 岁男性因左侧进行性眼眶肿块 6 个月就诊于 Farabi 眼科医院（伊朗）眼整形科。左侧眼眶有一大块浸润性肿块，延伸至眼球、眶周和附件，表现显着，其外观提示恶性肿瘤。我们的研究结果说服我们进行切除术和组织病理学评估，这些评估被报告为“未分化癌”。建议定期随访。2020 年 6 月，延迟了 3 个月，患者出现肿块复发，并伴有活动的活幼虫。检查显示，有大量蛆虫从溃疡性和恶臭的病灶中爬出。他说，由于担心感染 COVID-19，推迟了他的随访。患者立即机械移除幼虫，随后广泛局部切除肿块。患有附件组织癌的患者似乎更容易感染蝇蛆病，尽管它是一种不常见的疾病。由于 COVID-19 是一种持续流行且看不到尽头的流行病，因此应实施适当的协议，以防止这些高风险患者失去随访。检查显示，有大量蛆虫从溃疡性和恶臭的病灶中爬出。他说，由于担心感染 COVID-19，推迟了他的随访。患者立即机械移除幼虫，随后广泛局部切除肿块。患有附件组织癌的患者似乎更容易感染蝇蛆病，尽管它是一种不常见的疾病。由于 COVID-19 是一种持续流行且看不到尽头的流行病，因此应实施适当的协议，以防止这些高风险患者失去随访。检查显示，有大量蛆虫从溃疡性和恶臭的病灶中爬出。他说，由于担心感染 COVID-19，推迟了他的随访。患者立即机械移除幼虫，随后广泛局部切除肿块。患有附件组织癌的患者似乎更容易感染蝇蛆病，尽管它是一种不常见的疾病。由于 COVID-19 是一种持续流行且看不到尽头的流行病，因此应实施适当的协议，以防止这些高风险患者失去随访。患有附件组织癌的患者似乎更容易感染蝇蛆病，尽管它是一种不常见的疾病。由于 COVID-19 是一种持续流行且看不到尽头的流行病，因此应实施适当的协议，以防止这些高风险患者失去随访。患有附件组织癌的患者似乎更容易感染蝇蛆病，尽管它是一种不常见的疾病。由于 COVID-19 是一种持续流行且看不到尽头的流行病，因此应实施适当的协议，以防止这些高风险患者失去随访。