The utility for electron paramagentic resonance (EPR or ESR)-based radiation biodosimetry has received increasing recognition concerning its potential to assist in guiding the clinical management of medical countermeasures in individuals unwantedly exposed to injurious levels of ionizing radiation. Similar to any of the standard physical dosimetric methods currently employed for screening clinically significant radiation exposures, the EPR-based in vivo dosimetry approach would serve to complement and extend clinical assessments (e.g., blood analyses, cytogenetics, etc.), specifically to more accurately assign the extent of ionizing radiation exposure that individuals might have received. In the case of EPR biodosimetry of biological samples such as nails, teeth, and bones, the method has the capability of providing information on the physical dose at several specific bodily sites and perhaps additonal information on the homogeneity of the exposure as well as its overall magnitude. This information on radiation dose and distribution would be of significant value in providing medical management to given individuals at health risk due to radiation exposure. As these measurements provide information solely on physical measures of the radiation dose and not on the potential biological impact of a particular dose, they are complementary, albeit supplemental, to the array of currently available biologically based biodosimetry and clinical findings. In aggregate, these physical and biological measures of radiation exposure levels (dose) would most certainly provide additional, useful information for the effective medical management of radiation exposed individuals.

基于电子顺磁共振 (EPR 或 ESR) 的辐射生物剂量测定的效用已得到越来越多的认可，因为它有可能帮助指导对意外暴露于有害水平电离辐射的个人的医疗对策的临床管理。类似于目前用于筛选具有临床意义的辐射暴露的任何标准物理剂量学方法，基于 EPR 的体内剂量学方法将有助于补充和扩展临床评估（例如，血液分析、细胞遗传学等），特别是为了更准确地评估分配个人可能接受的电离辐射暴露程度。在对指甲、牙齿和骨骼等生物样品进行 EPR 生物剂量测定的情况下，该方法能够提供关于几个特定身体部位的物理剂量的信息，并且可能提供关于暴露均匀性及其总体量级的附加信息。这种关于辐射剂量和分布的信息对于为因辐射暴露而处于健康风险的特定个人提供医疗管理具有重要价值。由于这些测量仅提供有关辐射剂量的物理测量的信息，而不是特定剂量的潜在生物学影响的信息，因此它们是对当前可用的基于生物学的生物剂量学和临床研究结果的补充，尽管是补充。总的来说，这些辐射暴露水平（剂量）的物理和生物测量肯定会提供额外的、