ABSTRACT

Purpose

To report a case of unilateral acute foveolitis following COVID-19 vaccination.

Methods

A case report.

Results

A 24-year-old woman developed a sudden blurring of vision in the left eye (LE) 5 days after receiving the first dose of COVID-19 vaccine. Examination of the LE showed a visual acuity at 20/40, 2+ cells in the vitreous, and a small yellow-orange foveal subretinal lesion. Late-phase fluorescein angiography showed a mild diffuse retinal vascular leakage and a faint foveal hyperfluorescence. ICG angiography showed in the late-phase hypofluorescence of the centrofoveal lesion. OCT B-scan demonstrated a conical hyperreflective subfoveal lesion on the retinal pigment epithelium associated with disruption of the outer retinal layers. En-face OCT revealed granular hyperreflective specks mainly in the inner nuclear layer. Work-up results were unremarkable. The patient received oral prednisolone with subsequent full functional and anatomic recovery.

Conclusion

Foveolitis may rarely occur as a complication of COVID-19 vaccination.

中文翻译：

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COVID-19 疫苗接种后急性中央凹的多模式成像

摘要

目的

报告一例 COVID-19 疫苗接种后单侧急性中央凹炎病例。

方法

病例报告。

结果

一名 24 岁女性在接种第一剂 COVID-19 疫苗 5 天后，左眼 (LE) 突然出现视力模糊。LE 的检查显示视力为 20/40，玻璃体中有 2+ 个细胞，以及一个小的黄橙色中心凹视网膜下病变。晚期荧光素血管造影显示轻度弥漫性视网膜血管渗漏和微弱的中央凹高荧光。ICG 血管造影显示中央凹病变的晚期低荧光。OCT B 扫描显示与视网膜外层破坏相关的视网膜色素上皮上的圆锥形高反射中央凹下病变。正面 OCT 显示颗粒状高反射斑点主要位于内核层。检查结果不显着。患者接受口服泼尼松龙，随后完全功能和解剖学恢复。

结论

作为 COVID-19 疫苗接种的并发症，中央凹可能很少发生。