Objectives: This study sought to explore feasibility, acceptability, and preliminary effects of aerobic training (AT), mindfulness training (MT), or both (MT + AT) on cognitive function in older individuals at risk of dementia. Method: Participants were randomized to AT, MT, both, or usual care (UC). Z-scores of attention, verbal fluency, and episodic memory for non-demented adults (ZAVEN) were computed at baseline, end of treatment (EOT), and 6 months since baseline. Results: Of the 36 enrolled participants (12 M, 24 F, mean age = 70.1 years), 97% were retained in the study at 6 months. At EOT, MT had higher ZAVEN scores than UC (b = .43, P =.03) and AT (b = .26, P = .10), while no differences were seen with MT + AT. A similar pattern was observed at a 6 month follow-up (all P values = .10). Discussion: MT may improve cognitive function in older individuals at risk of dementia. These preliminary findings need to be confirmed in a fully powered RCT.

目的：本研究旨在探讨有氧训练（AT）、正念训练（MT）或两者（MT + AT）对有痴呆风险的老年人认知功能的可行性、可接受性和初步效果。方法：参与者被随机分配接受 AT、MT、两者或常规护理 (UC)。在基线、治疗结束 (EOT) 和基线后 6 个月计算非痴呆成人的注意力、语言流畅性和情景记忆 (ZAVEN) 的 Z 分数。结果：在 36 名登记参与者（12 名男性，24 名女性，平均年龄 = 70.1 岁）中，97% 的人在 6 个月时保留在研究中。在 EOT 时，MT 的 ZAVEN 分数高于 UC（b = .43，P = .03）和 AT（b = .26，P = .10），而 MT + AT 则没有差异。在 6 个月的随访中观察到类似的模式（所有P值 = .10）。讨论：MT 可以改善有痴呆风险的老年人的认知功能。这些初步发现需要在全面的随机对照试验中得到证实。