Klemm et al. examined the role of tumour-associated macrophages (TAMs) at different stages of brain metastasis in mouse models and found that targeting TAMs by inhibiting both CSF1R and STAT5 might have long-lasting efficacy and prevent resistance.

中文翻译：

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驯服脑转移瘤中的 TAM

克莱姆等人。检查了肿瘤相关巨噬细胞 (TAM) 在小鼠模型中脑转移不同阶段的作用，发现通过抑制 CSF1R 和 STAT5 来靶向 TAM 可能具有持久的疗效并预防耐药性。