Oncogene amplification is a major driver of tumorigenesis; yet, the mechanisms generating amplification are only partially understood. New research reports on the identification of a new focal amplification pattern termed ‘seismic amplification’ that is hypothesized to originate from recombination between extrachromosomal DNA circles.

中文翻译：

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解码癌基因扩增的复杂模式

癌基因扩增是肿瘤发生的主要驱动力；然而，产生放大的机制只是部分理解。新的研究报告确定了一种称为“地震放大”的新焦点放大模式，该模式被假设源于染色体外 DNA 环之间的重组。