Purpose: 

This proof-of-concept study compared lean mass (LM) between women with heart disease (HD) and without HD.

Methods: 

Fifty-six community-dwelling women were pair-matched by age. Heart disease was defined using criteria from the US Behavioral Risk Factor Surveillance System. Body composition was measured using multifrequency bioelectrical impedance analysis. Relative LM was calculated against height (kg/m²) as the lean mass index (LMI). Sarcopenia was defined as an LMI <15.0 kg/m². Strength was measured with a handgrip dynamometer, arm curl test, and chair stand test.

Results: 

Those with HD had significantly less absolute (38.2 ± 0.8 vs 43.5 ± 1.0 kg; P < .001) and relative (15.3 ± 0.3 vs 16.2 ± 0.3 kg/m², P = .015) LM compared with those without HD. Body mass was significantly greater for those without HD (76.1 ± 2.1 vs 68.4 ± 2.1 kg; P = .013) and there were no differences in fat mass. Upper body strength was significantly less and lower body strength was diminished but not significantly different in those with HD compared to those without HD (handgrip: P = .016; arm curl: P < .001; chair stand: P = .066).

Conclusions: 

In this group of community-dwelling women, those who reported a diagnosis of HD had significantly less LM than those without HD. Although neither group was classified as sarcopenic, women with HD were at greater risk due to lower relative LM. Based on our findings, during cardiac rehabilitation clinicians should counsel women regarding resistance exercise for maintenance of LM in addition to strength.

中文翻译：

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患有和不患有心脏病的女性去脂体重的比较

目的： 

这项概念验证研究比较了患有心脏病 (HD) 和未患心脏病 (HD) 的女性的瘦体重 (LM)。

方法： 

56 名居住在社区的女性按年龄配对。心脏病是使用美国行为危险因素监测系统的标准来定义的。使用多频生物电阻抗分析测量身体成分。相对 LM 是根据身高 (kg/m ² ) 计算的，作为瘦体重指数 (LMI)。肌肉减少症定义为 LMI <15.0 kg/m ²。通过握力计、臂弯举测试和椅子站立测试来测量力量。

结果： 

与无HD的患者相比，HD患者的绝对LM （38.2±0.8 vs 43.5±1.0 kg； P < .001）和相对LM（15.3±0.3 vs 16.2±0.3 kg/m ²，P = .015）明显较低。没有 HD 的人的体重明显更大（76.1 ± 2.1 vs 68.4 ± 2.1 kg；P = .013），并且脂肪量没有差异。与没有 HD 的患者相比，HD 患者的上半身力量明显减弱，下半身力量也减弱，但没有显着差异（握力： P = .016；手臂弯曲：P < .001；椅子站立：P = .066）。

结论： 

在这组居住在社区的女性中，那些报告诊断为 HD 的女性的 LM 明显低于那些没有 HD 的女性。尽管两组均未被归类为肌肉减少症，但患有 HD 的女性由于相对 LM 较低，因此面临更大的风险。根据我们的研究结果，在心脏康复期间，除了力量之外，临床医生还应该建议女性进行抗阻运动，以维持 LM 。