Purpose To evaluate the minimum number of visual fields (VFs) required to precisely predict future VFs in eyes with retinitis pigmentosa (RP). Methods A series of 12 VFs (Humphrey Field Analyzer 10–2 test (8.9 years in average) were analysed from 102 eyes of 52 patients with RP. The absolute error to predict the 12th VF using the prior 11 VFs was calculated in a pointwise manner, using the linear regression, and the 95% CI range was determined. Then, using 3–10 initial VFs, next VFs (4th to 11th VFs, respectively) were also predicted. The minimum number of VFs required for the mean absolute prediction error to reach the 95% CI was identified. Similar analyses were iterated for the second and third next VF predictions. Similar analyses were conducted using mean deviation (MD). Results In the pointwise analysis, the minimum number of VFs required to reach the 95% CI for the 12th VF was five (first and second next VF predictions) and six (third next VF prediction). For the MD analysis, three (first and second next VF predictions) and four (third next VF prediction) VFs were required to reach 95% CI for the 12th VF. Conclusions The minimum number of VFs required to obtain accurate predictions of the future VF was five or six in the pointwise analysis and three or four in the analysis with MD. Data are available upon reasonable request.

中文翻译：

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色素性视网膜炎患者视野数量与未来预测准确性之间的关系

目的 评估精确预测色素性视网膜炎 (RP) 眼未来 VF 所需的最小视野数 (VF)。方法 对 52 名 RP 患者的 102 只眼睛的一系列 12 个 VF（Humphrey Field Analyzer 10-2 测试（平均 8.9 年））进行分析。以逐点方式计算使用先前 11 个 VF 预测第 12 个 VF 的绝对误差，使用线性回归，确定 95% CI 范围。然后，使用 3-10 个初始 VF，还预测下一个 VF（分别为第 4 到 11 个 VF）。平均绝对预测误差所需的最小 VF 数量确定了达到 95% CI 的情况。对接下来的第二个和第三个 VF 预测进行了类似的分析。使用平均偏差 (MD) 进行了类似的分析。结果 在逐点分析中，达到 95% 所需的最小 VF 数量第 12 个 VF 的 CI 为 5 个（接下来的第一个和第二个 VF 预测）和 6 个（接下来的第三个 VF 预测）。对于 MD 分析，需要 3 个（接下来的第一个和第二个 VF 预测）和 4 个（接下来的第三个 VF 预测）VF第 12 个 VF 达到 95% CI 结论 在逐点分析中，获得对未来 VF 的准确预测所需的最小 VF 数量为 5 或 6，在 MD 分析中为 3 或 4。数据可根据合理要求提供。