The unveiling of MOF growth mechanism is hampered by the lack of fundamental knowledge about the very early stage of nucleation, especially the form and ratio of molecular species in the solution for crystal growth. Herein, we report the detection of growth species for a series of MOFs with mono-linker, Cu-MOF-2-BDC and Cu-MOF-2-NDC, and two linkers, MTV-MOF-2-(C₄H₄)_x, by high resolution ESI-MS, where a large variety of Cu-containing species are identified unambiguously. The solvent molecules such as H₂O, methanol and DMF participate in the formation of these species, other than ethanol. Furthermore, in the growth solution of MTV-MOF-2-(C₄H₄)_x, growth species containing two different organic linkers are observed. The feeding ratio is not the only factor controlling the distribution of growth species for MTV-MOFs, but also the solvent involves in coordination, an aspect usually overlooked previously.

由于缺乏关于成核早期阶段的基础知识，特别是晶体生长溶液中分子种类的形式和比例，阻碍了 MOF 生长机制的揭示。在此，我们报告了对一系列 MOF 的生长物种的检测，这些 MOF 具有单接头 Cu-MOF-2-BDC 和 Cu-MOF-2-NDC，以及两个接头 MTV-MOF-2-(C ₄ H ₄ ) _x，通过高分辨率 ESI-MS，可以明确识别出多种含铜物质。溶剂分子如 H ₂ O、甲醇和 DMF 参与了这些物质的形成，除了乙醇。此外，在 MTV-MOF-2-(C ₄ H ₄ ) _{x的生长溶液中}，观察到含有两种不同有机接头的生长物种。补料比不仅是控制 MTV-MOFs 生长物种分布的唯一因素，而且溶剂也参与了协调，这是以前通常被忽视的一个方面。