Cancer is one of the most common diseases to threaten human health. If individuals are diagnosed with malignant tumors via a single cell, medical workers are greatly advantageous to early diagnose and intervene in malignant tumors therapy. In this paper, we propose a fluorescence detection map to rapidly distinguish whether the chromosomes of a cell are normal or abnormal by detecting the fluorescent intensity of a single cell. Herein, we draw a map from a single cell with an abnormal number of chromosomes that is monitored in real time. Moreover, this way offers precise and prompt detection of the surviving of cancer cells at or near the site of the tumor after treatments for cancer, which can achieve personalized cancer diagnosis and therapy. Therefore, cancer recurrences and metastasis can be effectively identified, utilizing this ultrasensitive detection method of an abnormal chromosome number.

中文翻译：

---

通过增强波导中的荧光进行单细胞检测，用于癌症诊断和治疗

癌症是威胁人类健康的最常见疾病之一。如果个体通过单个细胞被诊断出患有恶性肿瘤，对于早期诊断和干预恶性肿瘤治疗，医务工作者将大有优势。在本文中，我们提出了一种荧光检测图谱，通过检测单个细胞的荧光强度来快速区分细胞染色体是正常还是异常。在这里，我们从具有实时监测的异常染色体数量的单个细胞中绘制了一张图。而且，这种方式可以准确、及时地检测出癌症治疗后肿瘤部位或附近的癌细胞的存活情况，从而实现个性化的癌症诊断和治疗。因此，可以有效识别癌症的复发和转移，