α-Hydroxy ketones are important building blocks in biological, pharmaceutical and synthetic chemistry. In this work, diverse α-hydroxy ketones were efficiently constructed through the CO₂-promoted hydration process of propargyl alcohols, which was catalyzed by a system consisted of economical CuSO₄·5H₂O and a green 1-butyl-3-methylimidazolium acetate ionic liquid. Particularly, this catalytic system exhibited excellent activity under atmospheric CO₂ or even mimetic flue gas (20 vol% of CO₂). Moreover, this system employed the lowest metal loading ever reported (0.004-0.25 mol%) meanwhile reached the highest turnover number (11700) for the target hydration reaction. Additionally, this is the first reported Cu catalytic system with reliable recyclability, which could be easily reused at least 6 times with yields higher than 85%.

α-羟基酮是生物、药物和合成化学中的重要组成部分。在这项工作中，通过由经济的 CuSO ₄ ·5H ₂ O 和绿色的 1-丁基-3-甲基咪唑鎓乙酸盐组成的体系催化，通过 CO ₂促进炔丙醇的水合过程有效地构建了多种 α-羟基酮。离子液体。特别是，该催化体系在大气 CO ₂甚至模拟烟气（20 vol% CO ₂）。此外，该系统采用了有史以来最低的金属负载量（0.004-0.25 mol%），同时达到了目标水合反应的最高周转数（11700）。此外，这是第一个报道的具有可靠可回收性的铜催化系统，可轻松重复使用至少 6 次，产率高于 85%。