Purpose

To investigate the effects of overnight orthokeratology (OK) lenses wear on the interocular axial length (AL) difference in anisomyopic children.

Methods

Sixty anisomyopic children (8–14 years old) were enrolled in this one-year prospective, randomised controlled study. Subjects were randomly assigned to wear OK lenses (OK group) or single-vision spectacles (control group). AL was monitored at baseline and every six months using an IOL Master biometer, and axial elongation and interocular AL differences were compared between the groups.

Results

In the control group, the more myopic eyes had similar axial elongation (0.36 ± 0.17 mm) to the less myopic eyes (0.37 ± 0.17 mm) at the one-year follow-up (P > 0.05). In the OK group, the less myopic eyes exhibited significantly greater axial elongation (0.24 ± 0.17 mm) than the more myopic eyes (0.13 ± 0.13 mm) at the one-year follow-up (P < 0.05). The mean interocular AL difference significantly decreased in the OK group over one year, from 0.47 ± 0.24 mm to 0.35 ± 0.22 mm (P < 0.05). However, the mean interocular AL difference decreased only slightly in the control group, from 0.56 ± 0.28 mm to 0.55 ± 0.28 mm (P > 0.05).

Conclusion

This randomised, controlled study demonstrated that OK reduces the interocular AL difference in anisomyopic children due to stronger myopic control of the more myopic eye.

中文翻译：

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通过角膜塑形术控制儿童屈光不正近视：一项为期一年的随机临床试验

目的

调查夜间角膜塑形术 (OK) 镜片配戴对屈光性近视儿童眼间轴长 (AL) 差异的影响。

方法

60 名屈光不正的儿童（8-14 岁）参加了这项为期一年的前瞻性随机对照研究。受试者被随机分配到佩戴 OK 镜片（OK 组）或单光眼镜（对照组）。使用 IOL Master 生物测量仪在基线和每六个月监测一次 AL，并比较各组之间的轴伸长率和眼间 AL 差异。

结果

在对照组中，在一年的随访中，较近视眼的眼轴伸长率 (0.36 ± 0.17 mm) 与较轻近视眼 (0.37 ± 0.17 mm) 相似（ P > 0.05 ）  。在 OK 组中，在一年的随访中，近视程度较轻的眼睛的眼轴伸长率 (0.24 ± 0.17 mm) 明显大于近视程度较高的眼睛 (0.13 ± 0.13 mm)（P < 0.05 ）  。OK 组的平均眼间 AL 差异在一年内显着下降，从 0.47 ± 0.24 mm 降至 0.35 ± 0.22 mm ( P  < 0.05)。然而，对照组的平均眼间 AL 差异仅略有下降，从 0.56 ± 0.28 mm 降至 0.55 ± 0.28 mm ( P  > 0.05)。

结论

这项随机对照研究表明，由于对近视度数更高的眼睛的近视控制更强，因此 OK 可降低异度近视儿童的眼间 AL 差异。